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RE: venom
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by TIMFRIEDE on October 24, 2000
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Yep, for the people studying K blockers, in polylepis(I,K, B and E), and the new MIT. Plus, the muscarinic toxins. Wicked sh@t bro. These toxins help to discover new protein receptors. They have no PLA's, no enzymes.
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Are there muscarines in mamba venom?
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by Craig on October 27, 2000
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Hi, Tim Freide, you mentioned muscarines in mamba venoms, Are these in any way related to the muscarines in the Ammanita mushroom family ?? ie: Ammanita pantherina, phalloides, muscarina (Magic Mushroom). I have heard about the euphoric effects of strong neurotoxins but never new the exact components, except for polypeptides which a freind said in certain variations or structure can be euphoric/hullucinogenic
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RE: Are there muscarines in mamba venom?
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by TIMFRIEDE on October 28, 2000
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Sorta Craig. Some mamba venoms have an affinty for muscarinic receptors(indirect G protein receptors), as opposed to nicotinic receptors(direct receptors). Muscarinic rec.'s are named because muscarine has an affinity for this receptor(M1-M5). Muscarine is a toxic alkaloid from Amanita muscaria. Some mamba fractions bind to M1 and M3 receptors. So far, mambas are the only venomous ophidians that have these qualities. Briefly, that's it. Thanks, Tim
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