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Anti-Coagulant of Garter Snakes
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by Viper_Boy on December 28, 2004
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There is a study on vampire bat saliva. Doctors are testing to see if vampire bat saliva can be used to prevent strokes or to minimize their effect on people. Vampire bats have an anti-coagulant in their saliva to keep blood from clotting while lapping up the blood from the incision they have made. Garter snakes also have an anti-coagulant in their saliva. If you have been bitten by a garter snake, then you know that the blood just doesn't want to stop for a while. I think that garter snakes could also hold a key to prevention of strokes and other problems with arteries. Strokes, heart attacks, and problems caused from blockages are all too common these days. My question is, has anyone ever done a study on garter snake saliva?
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RE: Anti-Coagulant of Garter Snakes
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by BGF on December 28, 2004
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We've done quite a bit on colubrid venoms. You can download the papers published to date from
http://www.venomdoc.com/publications.html
We haven't looked at American garter snakes (yet) but we have given the Asian relative Rhabdophis a good flogging and will be publishing a couple papers soon about the types of toxins. Some really nasty toxins in there, some of which quite concievably could be in the American garter snakes.
As for the potential for drug design and development, the venoms in the various 'colubrid' snakes are a potential goldmine.
Cheers
Bryan
www.venomdoc.com
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RE: Anti-Coagulant of Garter Snakes
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by SwampY on December 29, 2004
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I know at least one FDA approved heart medication uses an anticoagulant from cottonmouth venom.
Chad Minter
Venomous Snakes Of The Southeast
http://www.lulu.com/content/87197
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RE: Anti-Coagulant of Garter Snakes
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by wcoley on December 29, 2004
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Captopril is an FDA approved ACE inhibitor and it comes from the venom of the brazilian pit viper. There is also an FDA approved medication that was isolated from gila monster venom, but I'll have to look that one up.
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RE: Anti-Coagulant of Garter Snakes
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by GREGLONGHURST on December 29, 2004
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On the other side of the coagulant coin, there is, or at least was, a medication that helps blood coagulate that's derived from Malayan pit viper venom.
~~Greg~~
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RE: Anti-Coagulant of Garter Snakes
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by ALA_herp31 on December 30, 2004
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Someone told me that Science has been doing research on the Boomslang, (Disphilodus t. typus) as to the anticoagulants in their venom. Is this study still on going, or dose anyone know? I know they have done some studies on the possible cancer destroying agents in Copperhead, (Akistrodon c. contortrix) venom, it would be something if Copperhead venom holds the cure for cancer huu?...............Be safe ya'll, happy herping Wally
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RE: Anti-Coagulant of Garter Snakes
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by BGF on December 31, 2004
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Hi mate
We have just finished a massive sequencing effort and are in the process of writing up a whole slew of papers. We have a whole heap of different toxin types (including a dozen brand new toxin types) from the full breadth of the Colubroidea. From viper (Azemiops feae) to elapid (Oxyuranus microlepidotus) and all the colubrid families in between. Watch this space ;-)
Cheers
Bryan
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